Caulobacter crescentus has emerged as a premier model for studying bacterial cell cycle regulation due to its distinctive asymmetric division, which produces two morphologically and functionally ...

(Nanowerk News) By simulating the life cycle of a minimal bacterial cell — from DNA replication to protein translation to metabolism and cell division — scientists have opened a new frontier of ...

A simulated cell in the early stages of division. Left half shows membrane (green cubes), and ribosomes (yellow/purple) interwoven through in the cell’s chromosome (red). Right side shows all the ...

Polysome profiling (a technique that separates cell contents to reveal which mRNAs are actively being made into proteins) revealed that in cells lacking Pfk2, mRNAs for critical cell cycle regulators ...

For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how ...

Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists ...

Arteriovenous malformations, a hallmark of hereditary hemorrhagic telangiectasia, may be driven by endothelial cell-cycle acceleration via CDK6, suggesting potential for repurposing CDK6 inhibitors.

Microtubules, the dynamic filaments that form the cell's internal scaffolding, have long been viewed as mere passive structural supports. But a new study reveals they play a far more active signaling ...

The journey started with an enigma in the zebrafish embryo: some endothelial cells, actively involved in the initial stages of the development of the earliest blood vessels, were dividing in an ...

Researchers discovered a kinase-driven phosphorylation switch that activates DNA packaging machinery, aligning nucleosomes at ...